Silvia Mangia 5th Asia-Pacific NMR Symposium 2013

Silvia Mangia

Dr. Mangia is Assistant Professor in the Department of Radiology at the University of Minnesota. She got master degree in Physics (1999), a Ph.D. in Biophysics (2003) and the title of Specialist in Medical Physics (2005) at the University of Rome "La Sapienza" (Italy). Since 2004 she has been working at the Center for Magnetic Resonance Research (CMRR). The focus of Dr. Mangia’s career is the invention and refinement of Magnetic Resonance Imaging (MRI) and Spectroscopy (MRS) methods that can be translated into clinical settings to answer biomedically relevant questions that involve mainly (but are not limited to) the human brain. As a biophysicist, her research activity aims at providing quantitative measures of tissue metabolism, structure, and function. During her career Dr. Mangia has designed and conducted pivotal MR studies of brain energy utilization with MRI and MRS at high field. Focused on innovation and translational research, she utilizes various MR methods to characterize disease like diabetes, multiple sclerosis and Parkinson’s disease in vivo. She works in close collaboration with scientists from the Departments of Radiology, Neurology, Medicine, Biochemistry, Orthopaedics, and Biostatistics at the University of Minnesota, as well as from several other American and European Universities. Research Interests: - Novel MR contrasts based on rotating frame relaxation measurements, magnetization transfer and chemical exchange - Applications of novel MRI/MRS protocols for translational research (Parkinson’s disease, multiple sclerosis and diabetes) - Proton NMR Spectroscopy at high fields - Functional studies of human brain metabolism - Neurovascular coupling and neuro-glia interactions - Oxidative and non-oxidative brain metabolism - Measurements of blood flow with arterial spin labeling methods - Resting state fMRI

Abstracts this author is presenting: